Doctor's Best

Doctor's Best Benfotiamine 150 with BenfoPure 150 mg (120 Veggie Caps)

  • Doctor’s Best Benfotiamine helps maintain healthy cells in the presence of blood glucose, provides support against oxidative stress, and supports healthy aging.
  • Benfotiamine is a synthetic derivative of thiamin (Vitamin B1) belonging to the family of compounds known as allithiamines.
  • Benfotiamine is fat-soluble, and more bioavailable and physiologically active than thiamin.
  • Gluten Free / Non-GMO /Vegetarian / Vegan / Soy Free

What is Doctor’s Best Benfotiamine?
Benfotiamine (S-benzoylthiamine-O-monophosphate) is a synthetic derivative of thiamin (Vitamin B1) belonging to the family of compounds known as allithiamines. Benfotiamine is fat-soluble and more bioavailable and physiologically active than thiamin. Benfotiamine helps maintain healthy cells in the presence of blood glucose, provides support against oxidative stress, and supports healthy ageing.

How does it work?
Benfotiamine raises the blood level of thiamin pyrophosphate (TPP), the biologically active coenzyme of thiamin, and stimulates transketolase, a cellular enzyme essential for maintenance of normal glucose metabolic pathways. Benfotiamine can greatly improve thiamin status, especially in comparison with regular forms of thiamin. In a randomised, double-blind crossover trial comparing bioavailability of benfotiamine to that of thiamin mononitrate (the most common supplemental form of vitamin B1) in 12 individuals, benfotiamine caused an average 5-fold greater increase in blood thiamin levels than thiamin mononitrate, with a concomitant greater thiamin concentration in red blood cells. Benfotiamine is converted to S-benzoylthiamin (through removal of the O-monophosphate by the digestive tract), which readily passes through intestinal cells and is converted into thiamin.

Why take Best Benfotiamine?
Benfotiamine is fat-soluble and more bioavailable and physiologically active than thiamin. Benfotiamine helps maintain healthy cells in the presence of blood glucose, provides support against oxidative stress, and supports healthy ageing. Benfotiamine helps maintain healthy glucose metabolism by increasing blood and tissue levels of thiamine pyrophosphate (TPP), the biologically active co-enzyme form of thiamine. TPP acts as a co-enzyme for three critical enzymes involved in glucose metabolism: 1) transketolase, 2) pyruvate dehydrogenase, and 3) a-ketogutarate decarboxylase. The latter two enzymes are involved in utilising glucose for fuel. Thus, TTP is vital to the cell’s energy supply.

Safety
Consult your healthcare provider before use if you are taking any prescription medications or if you have a medical condition.

Disclaimer
Do not use if you are pregnant, nursing or under the age of 18. Those taking prescription medicines, with medical conditions or specific concerns about the suitability of our products in relation to these, should always consult their healthcare practitioner prior to using these supplements. If you experience any adverse reaction from taking any product discontinue use immediately and contact your healthcare practitioner. Do not exceed the stated dose. Keep out of reach of children. Do not use if the seal is compromised.
None of the above statements have been evaluated by the MHRA. By opening any of our products you acknowledge: This product is not intended to diagnose, treat, cure or prevent any disease. Ingestion of our supplements is entirely at users own risk.

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